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    <title>UMN Pharma Inc.</title>
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    <id>tag:www.umnpharma.com,2009-03-12:/en//5</id>
    <updated>2010-06-07T09:29:04Z</updated>
    
    <generator uri="http://www.sixapart.com/movabletype/">Movable Type Commercial 4.24-ja</generator>

<entry>
    <title>UMN Pharma Confirms Immunogenicity and Safety of Avian Influenza A (H5N1) Vaccine Manufactured from Cell-Culture, UMN-0501 in Phase II Clinical Trial</title>
    <link rel="alternate" type="text/html" href="http://www.umnpharma.com/en/2010/04/umn-pharma-confirms-immunogenicity-and-safety-of-avian-influenza-a-h5n1-vaccine-manufactured-from-ce.html" />
    <id>tag:www.umnpharma.com,2010:/en//5.144</id>

    <published>2010-04-20T09:26:49Z</published>
    <updated>2010-06-07T09:29:04Z</updated>

    <summary>UMN Pharma Inc. today announced Phase II...</summary>
    <author>
        <name>管理者</name>
        
    </author>
    
        <category term="R&amp;D" scheme="http://www.sixapart.com/ns/types#category" />
    
    
    <content type="html" xml:lang="ja" xml:base="http://www.umnpharma.com/en/">
        <![CDATA[UMN Pharma Inc. today announced Phase II clinical trial results for UMN-0501, UMN Pharma's avian influenza A (H5N1) vaccine manufactured by cell-culture.  Trial results confirmed that UMN-0501 provided dose-dependent immunogenicity against a wild-type strain of avian influenza A (H5N1) virus.  There is no serious adverse event and severe systemic adverse event during the study period.  UMN-0501 was well tolerated up to 135µg, <a href="http://www.umnpharma.com/en/pdf/100420E.pdf" target="_blank">please see here</a>]]>
        
    </content>
</entry>

<entry>
    <title>API and UMN Pharma Announce Formulation Process Collaboration</title>
    <link rel="alternate" type="text/html" href="http://www.umnpharma.com/en/2010/04/api-and-umn-pharma-announce-formulation-process-collaboration.html" />
    <id>tag:www.umnpharma.com,2010:/en//5.143</id>

    <published>2010-04-16T09:23:56Z</published>
    <updated>2010-06-07T09:32:02Z</updated>

    <summary>UMN Pharma Inc. and API Co., Ltd. today ...</summary>
    <author>
        <name>管理者</name>
        
    </author>
    
        <category term="Manufacturing" scheme="http://www.sixapart.com/ns/types#category" />
    
    
    <content type="html" xml:lang="ja" xml:base="http://www.umnpharma.com/en/">
        <![CDATA[UMN Pharma Inc. and API Co., Ltd. today announced that the two companies have signed an agreement forming a comprehensive business alliance focused on the formulation process of UMN-0501, UMN Pharma's influenza vaccine, manufactured using cell-culture, <a href="http://www.umnpharma.com/en/pdf/100416E.pdf" target="_blank">please see here</a>]]>
        
    </content>
</entry>

<entry>
    <title>IHI Corporation and UMN Pharma Announce Manufacturing Collaboration</title>
    <link rel="alternate" type="text/html" href="http://www.umnpharma.com/en/2010/01/ihi-corporation-and-umn-pharma-announce-manufacturing-collaboration.html" />
    <id>tag:www.umnpharma.com,2010:/en//5.128</id>

    <published>2010-01-26T04:00:00Z</published>
    <updated>2010-06-07T09:31:30Z</updated>

    <summary>IHI Corporation and UMN Pharma today exe...</summary>
    <author>
        <name>管理者</name>
        
    </author>
    
        <category term="Manufacturing" scheme="http://www.sixapart.com/ns/types#category" />
    
    
    <content type="html" xml:lang="ja" xml:base="http://www.umnpharma.com/en/">
        <![CDATA[IHI Corporation and UMN Pharma today executed an agreement for the formation of a joint venture focused on the production of drug substance for influenza vaccine through the use of cell culture. For more information, <a href="http://www.umnpharma.com/pdf/100126E.pdf" target="_blank">please see here</a>]]>
        
    </content>
</entry>

<entry>
    <title>UMN Pharma initiates phase II clinical trial for avian influenza A (H5N1) vaccine manufactured from cell-culture, UMN-0501.</title>
    <link rel="alternate" type="text/html" href="http://www.umnpharma.com/en/2009/10/umn-pharma-initiates-phase-ii-clinical-trial-for-avian-influenza-a-h5n1-vaccine-manufactured-from-ce.html" />
    <id>tag:www.umnpharma.com,2009:/en//5.121</id>

    <published>2009-10-05T06:52:51Z</published>
    <updated>2010-01-26T02:36:02Z</updated>

    <summary>UMN Pharma Inc. today announced initiati...</summary>
    <author>
        <name>管理者</name>
        
    </author>
    
        <category term="R&amp;D" scheme="http://www.sixapart.com/ns/types#category" />
    
    
    <content type="html" xml:lang="ja" xml:base="http://www.umnpharma.com/en/">
        <![CDATA[UMN Pharma Inc. today announced initiation of phase II clinical trials with UMN-0501, UMN's avian influenza A (H5N1) vaccine manufactured by cell-culture.The purpose of this clinical study is to evaluate immunogenicity, safety and optimal dose in 90 healthy young adults aged 20-40. Study results will be obtained by next February.&nbsp; For more information, please see <a href="http://www.umnpharma.com/pdf/091005E.pdf" target="_blank">here.</a>]]>
        
    </content>
</entry>

<entry>
    <title>Protein Sciences Corporation signs a contract which amounts to about 147 million dollars with U.S. Department of Health and Human Services for new way to make flu vaccine.</title>
    <link rel="alternate" type="text/html" href="http://www.umnpharma.com/en/2009/06/protein-sciences-corporation-signs-a-contract-which-amounts-to-about-147-million-dollars-with-us-dep.html" />
    <id>tag:www.umnpharma.com,2009:/en//5.109</id>

    <published>2009-06-29T10:03:41Z</published>
    <updated>2009-06-29T10:04:54Z</updated>

    <summary>Department of Health and Human Services ...</summary>
    <author>
        <name>管理者</name>
        
    </author>
    
        <category term="Others" scheme="http://www.sixapart.com/ns/types#category" />
    
    
    <content type="html" xml:lang="ja" xml:base="http://www.umnpharma.com/en/">
        <![CDATA[Department of Health and Human Services (HHS) announced on June 23 that the department has signed a new $35 million contract with Protein Sciences Corporation, Inc. for new way to make influenza vaccine.&nbsp; The contract could be extended up to five years at a total cost of approximately $147 million.&nbsp; HHS says that the Baculovirus Expression Vector System (BEVS) technology could help the nation respond to emerging infectious diseases such as seasonal and pandemic flu.<a href="http://www.hhs.gov/news/press/2009pres/06/20090623c.html" target="_blank">→HHS news release</a>]]>
        
    </content>
</entry>

<entry>
    <title>UMN Pharma Secures additional investment from IPEC.</title>
    <link rel="alternate" type="text/html" href="http://www.umnpharma.com/en/2009/02/umn-pharma-secures-additional-investment-from-ipec.html" />
    <id>tag:www.umnpharma.com,2009:/en//5.81</id>

    <published>2009-02-16T01:48:54Z</published>
    <updated>2009-04-10T09:27:16Z</updated>

    <summary>UMN Pharma Inc. today announced that it ...</summary>
    <author>
        <name>管理者</name>
        
    </author>
    
        <category term="Manufacturing" scheme="http://www.sixapart.com/ns/types#category" />
    
    
    <content type="html" xml:lang="ja" xml:base="http://www.umnpharma.com/en/">
        UMN Pharma Inc. today announced that it has secured an additional
investment of roughly $2 million as part of an existing construction
agreement with IHI Plant Engineering Corporation (headquartered in
Tokyo, hereinafter referred to as &quot;IPEC&quot;), an affiliate of IHI
Corporation. The investment was triggered by successful UMN-0501 Phase
I/II study results that met certain predetermined criteria. UMN Pharma
believes that this funding will serve to further strengthen the
collaboration with IPEC. 
        
    </content>
</entry>

<entry>
    <title>UMN Pharma presents favorable results from Phase I/II study of UMN-0501 at World Health Organization (WHO) pandemic influenza meeting.</title>
    <link rel="alternate" type="text/html" href="http://www.umnpharma.com/en/2009/02/umn-pharma-presents-favorable-results-from-phase-iii-study-of-umn-0501-at-world-health-organization.html" />
    <id>tag:www.umnpharma.com,2009:/en//5.80</id>

    <published>2009-02-13T01:48:19Z</published>
    <updated>2009-04-10T09:26:50Z</updated>

    <summary>UMN Pharma Inc. today announced that Shu...</summary>
    <author>
        <name>管理者</name>
        
    </author>
    
        <category term="R&amp;D" scheme="http://www.sixapart.com/ns/types#category" />
    
    
    <content type="html" xml:lang="ja" xml:base="http://www.umnpharma.com/en/">
        <![CDATA[UMN Pharma Inc. today announced that Shuichi Kanazashi, M.D. Ph.D.,
UMN's President &amp; CEO, presented favorable results from a Phase
I/II clinical study of UMN-0501, UMN Pharma's pandemic influenza
recombinant Hemagglutinin vaccine candidate, at the 5th World Health
Organization Meeting on Evaluation of Pandemic Influenza Prototype
Vaccines in Clinical Trials (Geneva, February 12-13). ]]>
        
    </content>
</entry>

<entry>
    <title>UMN Pharma Confirms Immunogenicity and Safety of UMN-0501 Pandemic Influenza Vaccine in Phase I/II Clinical Trials.</title>
    <link rel="alternate" type="text/html" href="http://www.umnpharma.com/en/2009/01/umn-pharma-confirms-immunogenicity-and-safety-of-umn-0501-pandemic-influenza-vaccine-in-phase-iii-cl.html" />
    <id>tag:www.umnpharma.com,2009:/en//5.79</id>

    <published>2009-01-15T01:47:02Z</published>
    <updated>2009-04-10T09:26:08Z</updated>

    <summary>Phase I/II clinical trials of UMN-0501, ...</summary>
    <author>
        <name>管理者</name>
        
    </author>
    
        <category term="R&amp;D" scheme="http://www.sixapart.com/ns/types#category" />
    
    
    <content type="html" xml:lang="ja" xml:base="http://www.umnpharma.com/en/">
        <![CDATA[Phase I/II clinical trials of UMN-0501, a new pandemic influenza
vaccine manufactured from cell culture, were launched in June of 2008.
Study results confirmed that UMN-0501 provided immunogenicity in the
group administered vaccine without alum against a natural strain of
pandemic influenza virus. The tolerability of UMN-0501 was good with no
serious or highly adverse side effects diagnosed by the principal
investigator.
<br />These results will be released at 5th WHO Meeting on Evaluation of
Pandemic Influenza Prototype Vaccines in Clinical Trials in February of
2009.
<br />
                              <br />
                              <span class="pt100"><img src="/imgs/icon_pdf_small.gif" alt="Acrobet PDF" border="0" width="22" height="16" /><a href="/pdf/090115E.pdf" target="_blank">News 
                              release PDF file.&nbsp; (124K) <br />
                        <br />
                        </a></span>
                        
                          
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<entry>
    <title>Relocation of Tokyo Head Office to Yokohama. Renamed as Yokohama Head Office.</title>
    <link rel="alternate" type="text/html" href="http://www.umnpharma.com/en/2008/12/relocation-of-tokyo-head-office-to-yokohama-renamed-as-yokohama-head-office.html" />
    <id>tag:www.umnpharma.com,2008:/en//5.78</id>

    <published>2008-12-22T01:46:12Z</published>
    <updated>2009-04-10T09:25:36Z</updated>

    <summary><![CDATA[&nbsp; ...]]></summary>
    <author>
        <name>管理者</name>
        
    </author>
    
        <category term="Others" scheme="http://www.sixapart.com/ns/types#category" />
    
    
    <content type="html" xml:lang="ja" xml:base="http://www.umnpharma.com/en/">
        <![CDATA[&nbsp; ]]>
        
    </content>
</entry>

<entry>
    <title>UMN-02 pharmacological study results published in the Journal of Pharmacology and Experimental Therapeutics.</title>
    <link rel="alternate" type="text/html" href="http://www.umnpharma.com/en/2008/10/umn-02-pharmacological-study-results-published-in-the-journal-of-pharmacology-and-experimental-thera.html" />
    <id>tag:www.umnpharma.com,2008:/en//5.77</id>

    <published>2008-10-01T01:45:10Z</published>
    <updated>2009-04-14T01:30:37Z</updated>

    <summary>UMN-02 pharmacological study results pub...</summary>
    <author>
        <name>管理者</name>
        
    </author>
    
        <category term="R&amp;D" scheme="http://www.sixapart.com/ns/types#category" />
    
    
    <content type="html" xml:lang="ja" xml:base="http://www.umnpharma.com/en/">
        <![CDATA[UMN-02 pharmacological study results published in the October, 2008 volume of <em>the Journal of Pharmacology and Experimental Therapeutics</em>,
a leading international academic journal, showed the involvement of
5-HT(2A) receptor activation in choline-deficient, 0.5% D,L-ethionine
supplemented (CDE) diet-induced acute pancreatitis in mice. This
research paper follows a previous presentation made at the annual
Digestive Disease Week (DDW) conference held in May of 2008 in the USA.
The data presented at DDW demonstrated the potential efficacy of
selective 5-HT(2A) antagonist in acute pancreatitis. The most recent
study results showed that UMN-02 ameliorated severe necrotizing acute
pancreatitis in mice by inhibiting key inflammatory responses. Based on
these experimental results, we believe that UMN-02, a highly specific
5-HT2A antagonist, could serve as a novel therapeutic for the treatment
of not only of acute edematous pancreatitis, but also for various
symptoms of pancreatitis. <br />
References <br /> Yamaguchi I, Hamada K, Yoshida M, Isayama H,
Kanazashi S, and Takeuchi K. Risperidone attenuates local and systemic
inflammatory responses to ameliorate diet-induced severe necrotic
pancreatitis in mice: it may provide a new therapy for acute
pancreatitis. <em>J. Pharmacol. Exp. Ther.</em> 2008 Oct. 1;[epub ahead of print].<br /><br /><a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed/18832108?ordinalpos=2&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum">http://www.ncbi.nlm.nih.gov/pubmed/18832108?ordinalpos=2&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum</a><br />]]>
        
    </content>
</entry>

<entry>
    <title>UMN Pharma begins preparations for construction of a manufacturing facility for UMN-0501, a pandemic influenza vaccine manufactured using a novel cell culture technique.</title>
    <link rel="alternate" type="text/html" href="http://www.umnpharma.com/en/2008/08/umn-pharma-begins-preparations-for-construction-of-a-manufacturing-facility-for-umn-0501-a-pandemic.html" />
    <id>tag:www.umnpharma.com,2008:/en//5.76</id>

    <published>2008-08-22T01:43:37Z</published>
    <updated>2009-04-10T09:23:51Z</updated>

    <summary>UMN Pharma Inc. announced that it has re...</summary>
    <author>
        <name>管理者</name>
        
    </author>
    
        <category term="Manufacturing" scheme="http://www.sixapart.com/ns/types#category" />
    
    
    <content type="html" xml:lang="ja" xml:base="http://www.umnpharma.com/en/">
        <![CDATA[UMN Pharma Inc. announced that it has reached a construction agreement
with IHI Plant Engineering Corporation, an affiliate of IHI
Corporation. This is the first step toward the construction of a
facility to manufacture UMN-0501, UMN's pandemic influenza vaccine
under development, produced using a cell culture technique. <br />
                              <br />
                              <span class="pt100"><img src="http://www.umnpharma.com/imgs/icon_pdf_small.gif" alt="Acrobet PDF" width="22" border="0" height="16" /><a href="http://www.umnpharma.com/pdf/080822E.pdf" target="_blank">News 
                              release PDF file.&nbsp; (108K) <br />
                        <br />
                        </a></span>
                        
                          
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    </content>
</entry>

<entry>
    <title>UMN Pharma initiates phase I/II trials for pandemic influenza vaccine manufactured from cell-culture, UMN-0501.</title>
    <link rel="alternate" type="text/html" href="http://www.umnpharma.com/en/2008/06/umn-pharma-initiates-phase-iii-trials-for-pandemic-influenza-vaccine-manufactured-from-cell-culture.html" />
    <id>tag:www.umnpharma.com,2008:/en//5.75</id>

    <published>2008-06-18T01:41:57Z</published>
    <updated>2009-04-10T09:23:19Z</updated>

    <summary>UMN Pharma Inc. today announced initiati...</summary>
    <author>
        <name>管理者</name>
        
    </author>
    
        <category term="R&amp;D" scheme="http://www.sixapart.com/ns/types#category" />
    
    
    <content type="html" xml:lang="ja" xml:base="http://www.umnpharma.com/en/">
        <![CDATA[<table id="NEWS2008" width="462" border="0" cellpadding="4" cellspacing="0"><tbody><tr></tr><tr><td class="pt120" valign="top" width="348" align="left">UMN Pharma Inc. today announced initiation of phase I/II clinical
trials in human subjects with UMN-0501, UMN's pandemic influenza
vaccine. In Japan, this is the "first-in-man" clinical study of a
pandemic influenza vaccine manufactured by cell-culture. The purpose of
this clinical study is to assess safety and efficacy in 125 healthy
adults aged 20-40. Study results will be obtained by the end of the
year. <br />
                              <br />
                              <span class="pt100"><img src="http://www.umnpharma.com/imgs/icon_pdf_small.gif" alt="Acrobet PDF" width="22" border="0" height="16" /><a href="http://www.umnpharma.com/pdf/080618E.pdf" target="_blank">News 
                              release PDF file.&nbsp; (39K) <br />
                        <br />
                        </a></span>
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</entry>

<entry>
    <title>UMN pandemic influenza vaccine, UMN-0501 designated as orphan drug.</title>
    <link rel="alternate" type="text/html" href="http://www.umnpharma.com/en/2008/06/umn-pandemic-influenza-vaccine-umn-0501-designated-as-orphan-drug.html" />
    <id>tag:www.umnpharma.com,2008:/en//5.74</id>

    <published>2008-06-10T01:40:23Z</published>
    <updated>2009-04-10T09:22:44Z</updated>

    <summary>UMN Pharma Inc. today announced that UMN...</summary>
    <author>
        <name>管理者</name>
        
    </author>
    
        <category term="R&amp;D" scheme="http://www.sixapart.com/ns/types#category" />
    
    
    <content type="html" xml:lang="ja" xml:base="http://www.umnpharma.com/en/">
        <![CDATA[UMN Pharma Inc. today announced that UMN-0501, a novel vaccine being
developed by UMN Pharma for pandemic influenza, has been granted orphan
drug designation by the Ministry of Health, Labour and Welfare.
UMN-0501 is a novel pandemic influenza vaccine manufactured from cell
culture using recombinant protein rather than the traditional method
that utilizes embryonated-egg culture. <br />
                              <br />
                              <span class="pt100"><img src="http://www.umnpharma.com/imgs/icon_pdf_small.gif" alt="Acrobet PDF" width="22" border="0" height="16" /><a href="http://www.umnpharma.com/pdf/080610E.pdf" target="_blank">News 
                              release PDF file.&nbsp; (72K) <br />
                        <br />
                        </a></span>
                        
                          
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<entry>
    <title>UMN Pharma presents at DIGESTIVE DESEASE WEEK 2008 in San Diego, California.</title>
    <link rel="alternate" type="text/html" href="http://www.umnpharma.com/en/2008/05/umn-pharma-presents-at-digestive-desease-week-2008-in-san-diego-california.html" />
    <id>tag:www.umnpharma.com,2008:/en//5.73</id>

    <published>2008-05-19T01:39:17Z</published>
    <updated>2009-04-13T03:09:45Z</updated>

    <summary>Researchers from UMN Pharma Inc. present...</summary>
    <author>
        <name>管理者</name>
        
    </author>
    
        <category term="R&amp;D" scheme="http://www.sixapart.com/ns/types#category" />
    
    
    <content type="html" xml:lang="ja" xml:base="http://www.umnpharma.com/en/">
        Researchers from UMN Pharma Inc. presented pharmacological study
results at the annual Digestive Disease Week conference demonstrating
the impact of UMN-02, a specific 5HT-2A receptor antagonist, on
choline-deficient ethionine-supplemented (CDE) diet-induced necrotizing
acute pancreatitis in mice. This presentation showed that UMN-02
ameliorated severe necrotizing acute pancreatitis in mice by inhibiting
key inflammatory responses. Based on these experimental results, we
believe that UMN-02 could serve as a novel therapeutic for the
treatment of acute pancreatitis.
UMN-02 is a highly specific 5HT-2A receptor antagonist being developed
by UMN Pharma Inc. for the treatment of acute pancreatitis.
Further details about our presentation can be found in the conference
proceedings from the DIGESTIVE DESEASE WEEK 2008. 
        
    </content>
</entry>

<entry>
    <title>UMN Pharma acquires factory site in Akita for the manufacturing of pandemic influenza vaccine.</title>
    <link rel="alternate" type="text/html" href="http://www.umnpharma.com/en/2008/04/umn-pharma-acquires-factory-site-in-akita-for-the-manufacturing-of-pandemic-influenza-vaccine.html" />
    <id>tag:www.umnpharma.com,2008:/en//5.72</id>

    <published>2008-04-30T01:37:47Z</published>
    <updated>2009-04-10T09:21:35Z</updated>

    <summary>This acquisition will allow UMN Pharma t...</summary>
    <author>
        <name>管理者</name>
        
    </author>
    
        <category term="Manufacturing" scheme="http://www.sixapart.com/ns/types#category" />
    
    
    <content type="html" xml:lang="ja" xml:base="http://www.umnpharma.com/en/">
        <![CDATA[This acquisition will allow UMN Pharma to build a manufacturing
facility for the production of UMN-0501, a pandemic influenza vaccine
being developed by UMN Pharma that will begin Phase I/II clinical
trials in June of this year.
<br />
                              <br />
                              <span class="pt100"><img src="/imgs/icon_pdf_small.gif" alt="Acrobet PDF" border="0" width="22" height="16" /><a href="/pdf/080430E.pdf" target="_blank">News 
                              release PDF file.&nbsp; (74K) <br />
                        <br />
                        </a></span>
                        
                          
                            <table border="0" cellpadding="3" cellspacing="0" class="table_news"><tbody><tr><td><span class="pt090"><a href="http://www.adobe.com/products/acrobat/readstep2.html" target="_blank"><img src="/imgs/icon_acrobat.gif" alt="Get Acrobat reader" border="0" width="88" height="31" /></a></span></td>
                            <td><span class="pt090">In order to view this file, you will need to have the following plug-in installed.</span></td></tr></tbody></table> ]]>
        
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