The results of pharmacological studies on UMN-02 published in the current volume of the Journal of Pharmacological Sciences, a leading Japanese academic journal, showed the involvement of 5-HT(2A) receptor activation in cerulein-induced acute pancreatitis in mice.
The research paper follows a previous presentation at the annual meeting of the Japanese Pharmacological Society held in March, 2007 and strongly suggests potential efficacy of selective 5-HT(2A) antagonists in acute pancreatitis.

References
Possible Involvement of Endogenous 5-HT in Aggravation of Cerulein-Induced Acute Pancreatitis in Mice